ScienceDirect - Cell Metabolism : Enlightening the adrenal gland

ScienceDirect - Cell Metabolism : Enlightening the adrenal gland


The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study (Ishida et al., 2005 [this issue of Cell Metabolism]) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway.